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Heterozygous mice harbor an Lgr5-EGFP-IRES-creERT2 "knock-in" allele that both abolishes Lgr5 gene function and expresses EGFP and CreERT2 fusion protein. When these mice mice are bred with mice containing a loxP-flanked sequence of interest, tamoxifen-inducible, Cre-mediated recombination will result in deletion of the floxed sequences in the Lgr5-expressing cells of the offspring. Se hela listan på sigmaaldrich.com Complete information for LGR5 gene (Protein Coding), Leucine Rich Repeat Containing G Protein-Coupled Receptor 5, including: function, proteins, disorders, pathways, orthologs, and expression. Gene information about ENSG00000139292 / LGR5 - leucine-rich repeat containing G protein-coupled receptor 5 We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. 2020-03-16 · 606667 - leucine-rich repeat-containing g protein-coupled receptor 5; lgr5 - g protein-coupled receptor 49; gpr49 - lgr5 LGR5, also named as GPR49, GPR67 and HG38, belongs to the G-protein coupled receptor 1 family. It is an orphan receptor.
Published as Clone RD42 . FAB8078P. 1 Citation. 2020-3-16 · Northern blot analysis detected major 4.3-kb and minor 2.4-kb LGR5 transcripts that were most abundant in skeletal muscle, with lower amounts in placenta, spinal cord, brain, adrenal, colon, stomach, and bone marrow. LGR5 Antibodies G protein-coupled receptor GPR49 has been reported to be expressed in brain, skeletal muscle, placenta, and spinal cord. ESTs have been isolated from normal human brain (amygdala), embryo, and placenta libraries and from human germ cell, uterus, and brain libraries.
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The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily.
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UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems.
GO annotations related to this gene include transmembrane signaling receptor activity and G-protein coupled receptor activity. An important paralog of this gene is LHCGR. …
Lgr5 homologues are facultative Wnt receptor components that mediate Wnt signal enhancement by soluble R-spondin proteins.
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Bioactivity. Show Size & Price. Mouse Lgr5/GPR49 Antibody . Published as Clone RD20 .
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LGR5 Gene - GeneCards | LGR5 Protein Här rapporterar vi att ett utsöndrat protein, Rspo2, uttrycks starkt i SMN: erna Lgr5 är en receptor av Rspo-proteiner i tarmkrypterna och hårsäckarna 26, 31 . Griseprotein Article [2021].